Description

2,3,4-Trifluorophenyl Isocyanate is a specialized fluorinated aromatic isocyanate building block, essential for introducing the trifluorophenyl moiety into advanced molecular architectures. Its value lies in enabling the synthesis of high-performance materials and active compounds with enhanced properties such as chemical stability, lipophilicity, and metabolic resistance. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries for developing next-generation products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Specialty Polymers & Resins: Serves as a monomer or cross-linking agent for producing high-performance polyurethanes, polyureas, and coatings with superior chemical and thermal resistance.
• Liquid Crystal & OLED Materials: A crucial precursor for synthesizing fluorinated components in electronic display materials, enhancing their stability and electro-optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex heterocycles and novel organic compounds via urea and carbamate formation.
• Surface Modification Agent: Used to functionalize materials and nanoparticles, imparting specific surface properties for advanced material science applications.

Basic Information

Product Name	2,3,4-Trifluorophenyl Isocyanate
CAS No.	190774-58-4
Molecular Formula	C7H3F3NO
Molecular Weight	180.10 g/mol
Synonyms	2,3,4-Trifluorophenyl isocyanate; 1-Isocyanato-2,3,4-trifluorobenzene; 2,3,4-Trifluorobenzene isocyanate; Isocyanic acid, 2,3,4-trifluorophenyl ester; 2,3,4-Trifluoro phenylisocyanate; 2,3,4-Trifluorophenylisocyanate; (2,3,4-Trifluorophenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluorophenyl Isocyanate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.