Description

2-Fluoro-6-(trifluoromethyl)phenyl isocyanate is a specialized aromatic isocyanate monomer featuring a unique fluorine-substituted phenyl ring. This compound is a critical building block in the synthesis of advanced polymers and agrochemicals, where its structure imparts enhanced chemical stability and specific reactivity. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic moieties to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a vital building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms contribute to lipophilicity and target binding affinity.
• Polymer & Resin Production: Used in the manufacture of polyurethanes and other specialty polymers, yielding materials with specific thermal, chemical, or surface properties.
• Ligand & Catalyst Development: Employed in organic and organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis and other advanced reactions.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluoroorganic chemistry and novel material science.
• Surface Modification Agent: Can be used to functionalize surfaces or materials with isocyanate groups for further chemical grafting or adhesion promotion.

Basic Information

Product Name	2-Fluoro-6-(trifluoromethyl)phenyl Isocyanate
CAS No.	190774-53-9
Molecular Formula	C8H3F4NO
Molecular Weight	205.11 g/mol
Synonyms	2-Fluoro-α,α,α-trifluoro-m-tolyl isocyanate; 1-Fluoro-3-isocyanato-2-(trifluoromethyl)benzene; 2-Fluoro-6-trifluoromethylphenyl isocyanate; m-Tolyl, 2-fluoro-α,α,α-trifluoro-, isocyanate; Isocyanic acid, 2-fluoro-6-(trifluoromethyl)phenyl ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(trifluoromethyl)phenyl Isocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, assay, and identity confirmation. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept sealed under a dry inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.45 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.