Description

4-Fluoro-2-Nitrophenyl Isocyanate is a versatile aromatic isocyanate building block, critical for the synthesis of advanced chemical intermediates. Its value lies in the precise reactivity of the isocyanate group and the strategic substitution pattern of the aromatic ring, enabling the creation of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing urea or carbamate functional groups.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and nitro groups contribute to biological activity and stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polyurethanes, coatings, and adhesives with enhanced performance characteristics.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and organic synthesis, facilitating the construction of diverse heterocyclic and functionalized aromatic compounds.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex colorants and functional dyes due to its reactive isocyanate group and electron-withdrawing substituents.

Basic Information

Product Name	4-Fluoro-2-Nitrophenyl Isocyanate
CAS No.	190774-51-7
Molecular Formula	C7H3FN2O3
Molecular Weight	182.11 g/mol
Synonyms	2-Nitro-4-fluorophenyl isocyanate; 4-Fluoro-2-nitrobenzenisocyanate; 1-Fluoro-4-isocyanato-3-nitrobenzene; Isocyanic acid, 4-fluoro-2-nitrophenyl ester; (4-Fluoro-2-nitrophenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Nitrophenyl Isocyanate is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.