Description

2-Bromo-4,6-Difluorophenyl Isocyanate is a highly reactive aromatic isocyanate derivative, serving as a critical building block for the synthesis of complex organic molecules. Its value lies in its ability to introduce both the isocyanate functional group and halogenated aromatic structure into target compounds, enabling the creation of novel materials with tailored properties. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and metabolic diseases.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, leveraging the difluorophenyl moiety for enhanced biological activity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing high-performance polyurethanes, polyureas, and specialty coatings with unique thermal and chemical resistance.
• Liquid Crystal & OLED Materials: Building block for creating advanced organic electronic materials, where the bromo and fluoro substituents fine-tune electronic properties and molecular alignment.
• Chemical Research & Development: Essential reagent in medicinal chemistry and process chemistry for constructing complex molecular architectures via urea and carbamate formation.
• Dye & Pigment Intermediate: Used in the synthesis of specialized colorants and photographic chemicals requiring halogenated aromatic structures.

Basic Information

Item	Detail
Product Name	2-Bromo-4,6-Difluorophenyl Isocyanate
CAS No.	190774-48-2
Molecular Formula	C7H2BrF2NO
Molecular Weight	233.99 g/mol
Synonyms	2-Bromo-4,6-difluorophenyl isocyanate; 1-Bromo-3,5-difluoro-2-isocyanatobenzene; Isocyanic acid, 2-bromo-4,6-difluorophenyl ester; 2-Bromo-4,6-difluorophenyl isocyanatobenzene; (2-Bromo-4,6-difluorophenyl)isocyanate; 2-Bromo-4,6-difluorobenzene isocyanate
EINECS	Contact for details

Quality Control

Our 2-Bromo-4,6-Difluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.