Description

4-Bromo-2-Chlorophenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block essential for advanced organic synthesis. Its primary value lies in its ability to introduce the isocyanate functional group into complex molecules, enabling the formation of ureas, carbamates, and other pharmacologically active heterocycles. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the phenyl isocyanate moiety contributes to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polyurethanes and polymers with tailored properties for high-performance coatings and materials.
• Chemical Research: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities for screening libraries.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic colorants and functional dyes.

Basic Information

Product Name	4-Bromo-2-Chlorophenyl Isocyanate
CAS No.	190774-47-1
Molecular Formula	C7H3BrClNO
Molecular Weight	232.46 g/mol
Synonyms	2-Chloro-4-bromophenyl isocyanate; 1-Bromo-3-chloro-4-isocyanatobenzene; 4-Bromo-2-chlorophenyl isocyanate; Isocyanic acid, 4-bromo-2-chlorophenyl ester; (4-Bromo-2-chlorophenyl)isocyanate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-Chlorophenyl Isocyanate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.