Description

Nir-641 n-Succinimidyl Ester* is a functionalized near-infrared (NIR) dye derivative designed for bioconjugation. This compound is a critical reagent for labeling biomolecules such as proteins, peptides, and antibodies with a stable, fluorescent NIR tag, enabling sensitive detection and imaging applications. It is primarily utilized by researchers and manufacturers in the fields of biotechnology, pharmaceutical development, and diagnostic assay production.

Application

• Bioconjugation and Protein Labeling: Covalent attachment to primary amines (-NH2) on antibodies, proteins, and peptides for fluorescence tagging.
• In Vivo and In Vitro Imaging: Synthesis of NIR fluorescent probes for deep-tissue imaging, tumor targeting, and cellular tracking studies.
• Diagnostic Assay Development: Manufacturing of fluorescent lateral flow assays (LFAs), ELISA kits, and other immunoassay components.
• Biomolecular Sensing: Construction of fluorescent biosensors for the detection of specific analytes or enzymatic activity.
• Drug Delivery Research: Labeling of nanoparticles, liposomes, or drug conjugates to monitor biodistribution and pharmacokinetics.
• Flow Cytometry and Microscopy: Preparation of fluorescent markers for cell sorting, analysis, and high-resolution imaging.

Basic Information

Product Name	Nir-641 n-Succinimidyl Ester*
CAS No.	190714-26-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NIR-641 NHS Ester; Nir 641 Succinimidyl Ester; Cyanine dye NHS ester 641; NIR-641 SE; IR-641 NHS; Heptamethine cyanine NHS ester (641 nm); Near-infrared fluorescent labeling reagent 641; 641 nm reactive dye
EINECS	Contact for details

Quality Control

Our Nir-641 n-Succinimidyl Ester* is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC purity analysis, spectroscopic verification (NMR, MS), and functional activity testing. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Extinction Coefficient	Contact for details
Fluorescence Emission Max	~641 nm
Water Content (KF)	≤ 1.0%
Functional Activity	Conforms (by labeling test)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.