Description

1-Piperidinecarboxylic Acid,4-[(Hydroxyimino)Methyl]-,1,1-Dimethylethyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to introduce constrained piperidine scaffolds and oxime functionalities into peptide backbones to enhance stability, bioavailability, and receptor selectivity.
• Protease Inhibitor Synthesis: Serves as a precursor in the creation of potent inhibitors for various proteolytic enzymes, relevant in antiviral and anticancer drug discovery.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and target engagement.
• Agrochemical Research: Utilized as an intermediate in the design and synthesis of novel herbicides and plant growth regulators with specific modes of action.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in university laboratories and CRO (Contract Research Organization) settings.

Basic Information

Product Name	1-Piperidinecarboxylic Acid,4-[(Hydroxyimino)Methyl]-,1,1-Dimethylethyl Ester
CAS No.	190446-85-6
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	tert-Butyl 4-(hydroxyiminomethyl)piperidine-1-carboxylate; 1-Boc-4-(hydroxyiminomethyl)piperidine; 4-(Hydroxyiminomethyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-formylpiperidine oxime; Boc-4-CPO; 4-Formylpiperidine-1-carboxylic acid tert-butyl ester oxime; 1-(tert-Butoxycarbonyl)-4-(hydroxyiminomethyl)piperidine
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylic Acid,4-[(Hydroxyimino)Methyl]-,1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure consistency and compliance with research-grade specifications. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.