Description

3-Pyridineacetonitrile,α-Hydroxy-2-Methyl-(9Ci) is a specialized pyridine derivative nitrile compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a nitrile and a hydroxyl group on the pyridine ring, enabling its use in constructing complex pharmacologically active molecules. This high-purity intermediate is essential for research and development chemists and process scale-up teams within the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine moiety is a common structural feature.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable compound for methodological studies in organic chemistry, including new reaction development and heterocyclic chemistry research.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers and advanced organic electronic materials.

Basic Information

Product Name	3-Pyridineacetonitrile,α-Hydroxy-2-Methyl-(9Ci)
CAS No.	190249-18-4
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	2-Methyl-2-hydroxy-2-(3-pyridyl)acetonitrile; α-Hydroxy-2-methyl-3-pyridineacetonitrile; (2-Hydroxy-2-methyl-2-pyridin-3-yl)acetonitrile; 3-Pyridineacetonitrile, α-hydroxy-2-methyl-; 2-Methyl-2-(pyridin-3-yl)-2-hydroxyacetonitrile; 2-Hydroxy-2-(3-pyridyl)propionitrile; (RS)-2-Hydroxy-2-(pyridin-3-yl)propionitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridineacetonitrile,α-Hydroxy-2-Methyl-(9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.