Description

tert-Butyl [4-(2-Aminoethyl)Pyridin-2-Yl]Carbamate is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a pyridine ring and a Boc-protected aminoethyl side chain, makes it an invaluable intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and cardiovascular diseases.
• Peptidomimetic Research: Used to introduce protected aminoethyl-pyridine motifs into peptide backbones, creating analogs with enhanced stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses producing specialized fine chemicals on a commercial scale.

Basic Information

Product Name	tert-Butyl [4-(2-Aminoethyl)Pyridin-2-Yl]Carbamate
CAS No.	190189-67-4
Molecular Formula	C12H19N3O2
Molecular Weight	237.30 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-(2-aminoethyl)-, 1,1-dimethylethyl ester; 4-(2-Aminoethyl)-2-pyridinecarboxylic acid tert-butyl ester; tert-Butyl 4-(2-aminoethyl)picolinate; Boc-protected 4-(2-aminoethyl)picolinic acid; 2-((tert-Butoxycarbonyl)amino)ethyl)isonicotinate; N-Boc-2-(4-pyridyl)ethylamine derivative; 190189-67-4; 4-(2-((tert-Butoxycarbonyl)amino)ethyl)pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl [4-(2-Aminoethyl)Pyridin-2-Yl]Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.