Description

3-Pyridinecarbonitrile, 5-(Chloromethyl)-, Monohydrochloride is a high-purity, functionalized pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its reactive chloromethyl and nitrile functional groups.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry and reaction pathways.
• Material Science: Potential monomer or additive in the synthesis of specialized polymers and functional materials.

Basic Information

Product Name	3-Pyridinecarbonitrile, 5-(Chloromethyl)-, Monohydrochloride
CAS No.	189936-27-4
Molecular Formula	C7H6ClN2•HCl
Molecular Weight	189.05 g/mol (Free base: 152.59 g/mol)
Synonyms	5-(Chloromethyl)nicotinonitrile hydrochloride; 5-(Chloromethyl)-3-cyanopyridine hydrochloride; 3-Cyano-5-(chloromethyl)pyridine hydrochloride; Nicotinonitrile, 5-(chloromethyl)-, monohydrochloride; 5-Chloromethyl-3-cyanopyridine HCl; 5-(Chloromethyl)pyridine-3-carbonitrile hydrochloride; (5-Chloromethyl-pyridin-3-yl)-cyanide hydrochloride
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarbonitrile, 5-(Chloromethyl)-, Monohydrochloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP-compliant manufacturing for pharmaceutical applications, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.