Description

1H-Pyrrolo[2,3-B]Pyridine-6-Carbonitrile is a high-value nitrogen-containing heterocyclic building block, specifically a fused pyrrolopyridine derivative bearing a cyano functional group. This compound is of significant interest for its role as a key synthetic intermediate in modern pharmaceutical discovery and advanced material science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial scaffold in the synthesis of kinase inhibitors, receptor antagonists, and other biologically active small molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its unique heterocyclic structure.
• Material Science Precursor: Acts as a building block for organic semiconductors, ligands for catalysis, and functional polymers.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-6-Carbonitrile
CAS No.	189882-33-5
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	6-Cyano-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile; 6-CN-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole-6-carbonitrile; 6-Cyano-7-azaindole; Pyrrolo[2,3-b]pyridine-6-carbonitrile; 189882-33-5; 6-Cyano-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white powder/crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.