Description

(4-Chloro-3-Pyridinyl)Methanol CAS NO 189449-41-0 is a versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, featuring both a reactive chloro substituent and a hydroxymethyl group, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(4-Chloro-3-Pyridinyl)Methanol
CAS No.	189449-41-0
Molecular Formula	C6H6ClNO
Molecular Weight	143.57 g/mol
Synonyms	4-Chloro-3-pyridinemethanol; 4-Chloro-3-(hydroxymethyl)pyridine; 3-Pyridinemethanol, 4-chloro-; (4-Chloro-3-pyridyl)methanol; 4-Chloro-pyridin-3-yl-methanol; 4-Chloro-3-pyridylcarbinol; 4-Chloro-3-hydroxymethylpyridine; 189449-41-0
EINECS	Contact for details

Quality Control

Our (4-Chloro-3-Pyridinyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications, ensuring reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.