Description

3H-Spiro[Isobenzofuran-1,3'-Piperidin]-3-One CAS NO 189321-67-3 is a high-purity, heterocyclic organic compound featuring a unique spirocyclic architecture that combines isobenzofuran and piperidine motifs. This structural complexity makes it a critical intermediate and building block in advanced organic synthesis, particularly for developing novel pharmacologically active molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating new therapeutic agents and complex chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other bioactive molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to introduce the spirocyclic core into larger, more complex molecular frameworks.
• Agrochemical Development: Potential intermediate in the research and development of new active ingredients for crop protection products.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3H-Spiro[Isobenzofuran-1,3'-Piperidin]-3-One
CAS No.	189321-67-3
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	Spiro[isobenzofuran-1(3H),3'-piperidin]-3-one; 1',3'-Dihydrospiro[isobenzofuran-1,4'-piperidin]-3-one; 3H-Spiro[2-benzofuran-1,3'-piperidine]-3-one; 3-Oxospiro[isobenzofuran-1(3H),3'-piperidine]; Spiro(isobenzofuran-1(3H),3'-piperidin)-3-one; 189321-67-3; AKOS005158529
EINECS	Contact for details

Quality Control

Our 3H-Spiro[Isobenzofuran-1,3'-Piperidin]-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.