Description

tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate is a high-value, complex heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its critical role in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. Pharmaceutical R&D teams and fine chemical manufacturers need this precise spirocyclic scaffold to construct potential drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in hit-to-lead and lead optimization programs.
• Protease Inhibitor Development: Serves as a core structural element in the design of potential protease inhibitors.
• Kinase Inhibitor Synthesis: Employed in the construction of complex molecules targeting various kinase enzymes.
• Chemical Biology Probes: Utilized to create specialized molecular tools for studying biological pathways and protein function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology studies.

Basic Information

Product Name	tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate
CAS No.	189320-46-5
Molecular Formula	C18H22N2O3
Molecular Weight	314.38 g/mol
Synonyms	1-Boc-2',4'-dihydro-1'H-spiro[piperidine-3,3'-quinoline]-2'-one; 1-(tert-Butoxycarbonyl)-2',4'-dihydrospiro[piperidine-3,3'-quinoline]-2'(1'H)-one; tert-Butyl 2-oxo-1,4-dihydrospiro[piperidine-3,3'-quinoline]-1-carboxylate; Spiro[piperidine-3,3'-quinoline]-1-carboxylic acid, 2',4'-dihydro-2'-oxo-, 1,1-dimethylethyl ester; 189320-46-5; 1-N-Boc-2-oxo-1,2,3,4-tetrahydrospiro[quinoline-3,3'-piperidine]; Boc-protected spiroquinolinone piperidine.
EINECS	Contact for details

Quality Control

Our tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Piperidine-3,3'-Quinoline]-1-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.