Description

n-Benzyl-3,5,6-Trifluoropyridin-2-Amine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique trifluoromethyl-substituted pyridine core, which is essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Precursor: Employed in the creation of specialty polymers, liquid crystals, and electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probe: Serves as a versatile scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis Building Block: Provides a functionalized pyridine core for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis.

Basic Information

Product Name	n-Benzyl-3,5,6-Trifluoropyridin-2-Amine
CAS No.	189281-25-2
Molecular Formula	C12H10F3N2
Molecular Weight	230.21 g/mol
Synonyms	2-Amino-3,5,6-trifluoro-N-benzylpyridine; N-Benzyl-3,5,6-trifluoropyridin-2-amine; 3,5,6-Trifluoro-N-(phenylmethyl)-2-pyridinamine; 2-Pyridinamine, 3,5,6-trifluoro-N-(phenylmethyl)-; (3,5,6-Trifluoropyridin-2-yl)(benzyl)amine; Benzyl(3,5,6-trifluoropyridin-2-yl)amine
EINECS	Contact for details

Quality Control

Our n-Benzyl-3,5,6-Trifluoropyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.