Description

Cyclobutanecarboxylic Acid, 1-Amino-3-Phosphono-, cis- (9Ci) is a specialized, high-purity organophosphorus compound featuring a unique cis-configured cyclobutane backbone. This molecule is valued for its role as a sophisticated building block and ligand precursor in advanced chemical synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, or plant growth regulators that leverage its phosphonic acid functionality.
• Ligand for Catalysis: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Biochemical Research: Employed in the study of enzyme inhibitors or as a molecular probe due to its structural mimicry of natural phosphonates.
• Material Science: Potential monomer or additive for specialty polymers requiring specific thermal or chemical resistance properties.
• Academic & Industrial R&D: Fundamental building block in exploratory organic synthesis for constructing complex, strained-ring systems.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Amino-3-Phosphono-, cis- (9Ci)
CAS No.	189143-40-6
Molecular Formula	C5H10NO5P
Molecular Weight	195.11 g/mol
Synonyms	cis-1-Amino-3-phosphonocyclobutanecarboxylic acid; (1R,3S)-1-Amino-3-phosphonocyclobutanecarboxylic acid; (1S,3R)-1-Amino-3-phosphonocyclobutanecarboxylic acid; APCB; Cyclobutane-1-amino-3-phosphonocarboxylic acid; 1-Amino-3-phosphonocyclobutanecarboxylic acid, cis-; NSC 339288
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxylic Acid, 1-Amino-3-Phosphono-, cis- (9Ci) is produced and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through comprehensive analytical protocols including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.