Description

(4-Iodo-Benzyl)-Carbamic Acid tert-Butyl Ester is a versatile and high-purity chemical building block, specifically a Boc-protected amino derivative. This compound is critical for researchers and manufacturers requiring a protected intermediate for the synthesis of complex organic molecules and active pharmaceutical ingredients (APIs). It is primarily utilized in pharmaceutical R&D, agrochemical development, and advanced material science for constructing peptide mimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating targeted therapies.
• Peptidomimetic Synthesis: Serves as a protected precursor for introducing iodobenzyl-modified amino acid structures into peptides and peptide-like molecules.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides where specific aromatic iodine substitutions are required.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for studying biological pathways and protein interactions.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and advanced organic materials.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.

Basic Information

Product Name	(4-Iodo-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	189132-01-2
Molecular Formula	C12H16INO2
Molecular Weight	333.17 g/mol
Synonyms	N-Boc-4-iodobenzylamine; tert-Butyl (4-iodobenzyl)carbamate; N-(tert-Butoxycarbonyl)-4-iodobenzylamine; Boc-4-Iodo-Bn-NH2; 1-[(tert-Butoxycarbonyl)amino]methyl-4-iodobenzene; 4-Iodo-N-(Boc)benzylamine; (4-Iodophenyl)methanamine, N-[(1,1-dimethylethoxy)carbonyl]-; BOC-4-I-BZL-NH2
EINECS	Contact for details

Quality Control

Our (4-Iodo-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.