Description

tert-Butyl 4-(4-Amino-2-Fluorophenyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core with both amino and fluoro substituents. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in medicinal chemistry.
• API Development: Used in research and process development for new Active Pharmaceutical Ingredients (APIs).
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and derivatization in organic synthesis.
• CNS Drug Research: Applied in the development of compounds targeting neurological and psychiatric conditions.
• Oncology Research: Utilized in the creation of potential anti-cancer agents and targeted therapies.
• Academic & Industrial R&D: Employed in research laboratories for method development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	tert-Butyl 4-(4-Amino-2-Fluorophenyl)Piperidine-1-Carboxylate
CAS No.	188975-15-7
Molecular Formula	C16H23FN2O2
Molecular Weight	294.37 g/mol
Synonyms	1-Boc-4-(4-Amino-2-fluorophenyl)piperidine; 4-(4-Amino-2-fluorophenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(4-amino-2-fluorophenyl)piperidine; tert-Butyl 4-(4-amino-2-fluorophenyl)-1-piperidinecarboxylate; 4-(4-Amino-2-fluorophenyl)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-Amino-2-fluorophenyl)piperidine; Boc-4-(4-Amino-2-fluorophenyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Amino-2-Fluorophenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.