Description

D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester is a specialized anhydro sugar derivative with the CAS registry number 188922-95-4. This high-purity chiral building block is critical for synthetic chemists developing novel pharmaceuticals and fine chemicals, offering a unique, constrained sugar scaffold. It is primarily utilized in research and development for the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of nucleoside and nucleotide analogs for antiviral and anticancer therapies.
• Organic Synthesis Building Block: Used in the construction of complex, stereodefined natural products and novel chemical entities in medicinal chemistry.
• Carbohydrate Chemistry Research: Serves as a model compound in studies of anhydro sugar reactivity, ring-opening reactions, and glycosylation mimicry.
• Fine Chemical Production: Employed in the pilot-scale synthesis of specialty chemicals requiring specific sugar-based architectures.
• Bioconjugate Development: Potential use in creating chemically modified biomolecules for diagnostic or therapeutic applications.

Basic Information

Product Name	D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester
CAS No.	188922-95-4
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	Methyl 2,3-anhydro-4,5-dideoxy-D-threo-pentonate; 2,3-Anhydro-4,5-dideoxy-D-threo-pentonic acid methyl ester; D-threo-2,3-Anhydro-4,5-dideoxypentonic acid methyl ester; Methyl D-threo-2,3-anhydro-4,5-dideoxypentonate; Anhydro sugar ester; 188922-95-4; Methyl 2,3-anhydro-4,5-dideoxy-D-threo-pentonate
EINECS	Contact for details

Quality Control

Every batch of D-Threo-Pentonic Acid, 2,3-Anhydro-4,5-Dideoxy-, Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A Certificate of Analysis (COA) detailing specifications such as assay, chiral purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.