Description

2(1H)-Pyridinone, 5-B-D-Ribofuranosyl- 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)Pyridin-2(1H)-One is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Proteomics & Genomics: Serves as a modified nucleoside in the development of probes and tools for genetic research.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug candidate efficacy and safety profiles.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical manufacturing.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex, high-value organic molecules.

Basic Information

Product Name	2(1H)-Pyridinone, 5-B-D-Ribofuranosyl- 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)Pyridin-2(1H)-One
CAS No.	188871-50-3
Molecular Formula	C15H19NO8
Molecular Weight	341.31 g/mol
Synonyms	5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-2(1H)-one; 5-β-D-Ribofuranosyl-2(1H)-pyridinone; 5-(β-D-Ribofuranosyl)-2-pyridinone; 5-Ribofuranosyl-2-pyridone; 5-(β-D-Ribofuranosyl)pyridin-2(1H)-one; 2-Hydroxy-5-(β-D-ribofuranosyl)pyridine; 5-(β-D-Ribosyl)-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyridinone, 5-B-D-Ribofuranosyl- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP guidelines. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.