Description

Pentafluorophenylpyridine-2-Carboxylate is a high-value, multi-functional chemical building block characterized by its unique perfluorinated aromatic system. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its fluorine content for enhanced bioactivity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic ring.
• Fluorinated Building Block: A versatile reagent for introducing pentafluorophenyl groups into target molecules to modify solubility, lipophilicity, and metabolic stability.
• Chemical Biology Probes: Useful in the design of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Item	Detail
Product Name	Pentafluorophenylpyridine-2-Carboxylate
CAS No.	188837-53-8
Molecular Formula	C13H4F5NO2
Molecular Weight	301.17 g/mol
Synonyms	2-Pyridinecarboxylic acid, pentafluorophenyl ester; Pentafluorophenyl 2-pyridinecarboxylate; Pentafluorophenyl 2-picolinate; 2-Picolinic acid pentafluorophenyl ester; PFP-2-picolinate; CAS 188837-53-8; Pentafluorophenyl picolinate
EINECS	Contact for details

Quality Control

Our Pentafluorophenylpyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.