Description

Methyl 3-Bromo-5-Iodobenzoate is a high-purity, multi-halogenated aromatic ester building block of significant interest in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides with specific modes of action.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and extended π-conjugated systems.
• Ligand Preparation: Functionalization point for creating sophisticated chelating ligands used in homogeneous catalysis.
• Chemical Biology: Useful for incorporating halogenated aromatic probes into molecules for imaging or biochemical studies.

Basic Information

Product Name	Methyl 3-Bromo-5-Iodobenzoate
CAS No.	188813-07-2
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Benzoic acid, 3-bromo-5-iodo-, methyl ester; Methyl 3-bromo-5-iodobenzoate; 3-Bromo-5-iodobenzoic acid methyl ester; Methyl m-bromo-m'-iodobenzoate; 188813-07-2; Methyl 3-Br-5-I-benzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.