Description

3,4-Pyrrolidinediol, 2-(Hydroxymethyl)-5-(3-Pyridinyl)-, (2R,3R,4S,5S)- is a high-purity, stereochemically defined pyrrolidine derivative with significant synthetic utility. This compound serves as a crucial chiral building block and advanced intermediate in the development of novel pharmaceutical agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex molecules targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Serves as a precursor for catalysts or ligands used in stereoselective chemical transformations.
• Biochemical Research: Potential use as a tool compound or probe in enzymatic and receptor binding studies.
• Academic Research: Employed in synthetic organic chemistry for the construction of complex nitrogen-containing heterocycles.

Basic Information

Product Name	3,4-Pyrrolidinediol, 2-(Hydroxymethyl)-5-(3-Pyridinyl)-, (2R,3R,4S,5S)-
CAS No.	188744-99-2
Molecular Formula	C10H14N2O3
Molecular Weight	210.23 g/mol
Synonyms	(2R,3R,4S,5S)-2-(Hydroxymethyl)-5-(3-pyridinyl)-3,4-pyrrolidinediol; (2R,3R,4S,5S)-5-(3-Pyridinyl)-2-(hydroxymethyl)pyrrolidine-3,4-diol; 1-Deoxynojirimycin derivative; Dihydroxypyrrolidine pyridine methanol; Polyhydroxylated pyrrolidine; Iminosugar analog; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3,4-Pyrrolidinediol, 2-(Hydroxymethyl)-5-(3-Pyridinyl)-, (2R,3R,4S,5S)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.