Description

3-Iodoisonicotinic Acid Methyl Ester is a high-purity iodinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which facilitates key coupling reactions and functional group transformations essential for creating complex molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings for carbon-carbon bond formation.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to the iodine moiety.
• Organic Synthesis: A versatile reagent for introducing the iodinated isonicotinate group into target molecules.

Basic Information

Product Name	3-Iodoisonicotinic Acid Methyl Ester
CAS No.	188677-49-8
Molecular Formula	C7H6INO2
Molecular Weight	263.03 g/mol
Synonyms	Methyl 3-iodopyridine-4-carboxylate; 3-Iodo-4-pyridinecarboxylic acid methyl ester; 3-Iodoisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 3-iodo-, methyl ester; Methyl 3-iodoisonicotinate; 3-Iodopyridine-4-carboxylic acid methyl ester; Isonicotinic acid, 3-iodo-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Iodoisonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.