Description

4-Chloro-n-[2-[[5-(Trifluoromethyl)-2-Pyridinyl]Sulfonyl]Ethyl]Benzamide CAS NO 188591-46-0 is a high-purity, advanced pharmaceutical intermediate featuring a distinct trifluoromethylpyridine sulfonamide core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for complex small molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of potential drug candidates, especially those targeting enzyme inhibition.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the trifluoromethyl and sulfonyl groups.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in the study of protein-protein interactions and enzyme function due to its specific binding motifs.
• Material Science Research: Investigated for the creation of specialized polymers or coatings with unique surface properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Item	Details
Product Name	4-Chloro-n-[2-[[5-(Trifluoromethyl)-2-Pyridinyl]Sulfonyl]Ethyl]Benzamide
CAS No.	188591-46-0
Molecular Formula	C15H12ClF3N2O3S
Molecular Weight	392.78 g/mol
Synonyms	4-Chloro-N-[2-({[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}ethyl)benzamide; 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide; Benzamide, 4-chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-; 188591-46-0; UNII-9J0H8V8A4M; 9J0H8V8A4M
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-n-[2-[[5-(Trifluoromethyl)-2-Pyridinyl]Sulfonyl]Ethyl]Benzamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical-grade material is supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids/bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.