Description

1-Pyrrolidineaceticacid,4-Amino-2-Carboxy-,(2S-Cis)-(9Ci) is a high-purity, non-natural amino acid derivative featuring a unique pyrrolidine backbone with both amino and carboxylic acid functional groups. This compound is a critical chiral building block for the synthesis of complex pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, enzyme modulators, and other active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Serves as a constrained proline analog for constructing novel peptide-like structures in medicinal chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal complexation studies.
• Agrochemical Development: A building block for creating novel compounds with potential herbicidal or insecticidal activity.
• Bioconjugation: The reactive functional groups enable its use in linking molecules for diagnostic or therapeutic applications.
• Chemical Biology Probes: Incorporation into molecules designed to study biological pathways and protein function.

Basic Information

Product Name	1-Pyrrolidineaceticacid,4-Amino-2-Carboxy-,(2S-Cis)-(9Ci)
CAS No.	188578-53-2
Molecular Formula	C7H12N2O4
Molecular Weight	188.18 g/mol
Synonyms	(2S,4S)-4-Aminopyrrolidine-2-carboxylic acid; (2S,4S)-4-Amino-2-carboxypyrrolidine; cis-4-Amino-L-proline; 4-Amino-L-proline (cis); 4-Aminoproline; (2S,4S)-4-Aminopyrrolidine-2-carboxylic acid hydrochloride; 1-Pyrrolidineacetic acid, 4-amino-2-carboxy-, (2S-cis)-; L-4-Aminoproline
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidineaceticacid,4-Amino-2-Carboxy-,(2S-Cis)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.