Description

3-Pyridinecarbonitrile,1,4,5,6-Tetrahydro-5-Hydroxy-1-Methyl-(9Ci) is a specialized heterocyclic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a fused tetrahydro-pyridine ring with hydroxyl and nitrile functionalities, makes it a valuable precursor for constructing complex pharmacophores. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. Its role is critical in the synthesis of novel active ingredients, where it serves as a key intermediate for introducing specific molecular complexity and polarity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Reagent: Serves as a versatile precursor for synthesizing more complex pyridine and piperidine derivatives through reactions at the nitrile and hydroxyl groups.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Academic & Institutional Research: Used in universities and research institutes for methodological studies and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Pyridinecarbonitrile,1,4,5,6-Tetrahydro-5-Hydroxy-1-Methyl-(9Ci)
CAS No.	188242-02-6
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	5-Hydroxy-1-methyl-1,4,5,6-tetrahydro-3-pyridinecarbonitrile; 1-Methyl-5-hydroxy-1,2,3,6-tetrahydro-3-pyridinecarbonitrile; 1-Methyl-5-hydroxy-3-cyano-1,2,3,6-tetrahydropyridine; 3-Cyano-1-methyl-5-hydroxy-1,2,3,6-tetrahydropyridine; 5-Hydroxy-1-methyl-3-cyano-1,2,3,6-tetrahydropyridine; 1,4,5,6-Tetrahydro-5-hydroxy-1-methyl-3-pyridinecarbonitrile; (9CI) Index name
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinecarbonitrile,1,4,5,6-Tetrahydro-5-Hydroxy-1-Methyl-(9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.