Description

3-Oxa-7-Azabicyclo[4.1.0]Heptane-7-Carboxylic Acid, Ethyl Ester is a specialized bicyclic heterocyclic compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique azabicyclo structure makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing constrained heterocyclic scaffolds.
• Medicinal Chemistry Research: Used as a versatile building block for constructing novel chemical libraries in drug discovery programs targeting various disease pathways.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) and generic APIs.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for the production of specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-Oxa-7-Azabicyclo[4.1.0]Heptane-7-Carboxylic Acid, Ethyl Ester
CAS No.	188172-03-4
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	Ethyl 3-Oxa-7-azabicyclo[4.1.0]heptane-7-carboxylate; 7-Ethoxycarbonyl-3-oxa-7-azabicyclo[4.1.0]heptane; 7-Azabicyclo[4.1.0]heptane-7-carboxylic acid, 3-oxa-, ethyl ester; Ethyl 7-azabicyclo[4.1.0]heptane-3-oxa-7-carboxylate; Bicyclic aziridine ethyl ester; Aziridine-fused oxazine derivative
EINECS	Contact for details

Quality Control

Our production of 3-Oxa-7-Azabicyclo[4.1.0]Heptane-7-Carboxylic Acid, Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.