Description

D-Isovaline, 3-Hydroxy-, Ethyl Ester, (4R)-Rel- (9Ci) is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This chiral building block is valued for its unique stereochemistry and functional groups, enabling the construction of complex molecular architectures. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including peptidomimetics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, chiral active ingredients for crop protection products.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands or catalysts used in stereoselective synthesis.
• Biochemical Research: Employed in studies of amino acid metabolism, neurotransmission, and as a tool compound in neuropharmacology.
• Peptide Chemistry: Acts as a modified amino acid residue for incorporating non-natural elements into peptide sequences to alter stability and bioactivity.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	D-Isovaline, 3-Hydroxy-, Ethyl Ester, (4R)-Rel- (9Ci)
CAS No.	188124-80-3
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(4R)-rel-3-Hydroxy-D-isovaline ethyl ester; Ethyl (2R)-2-amino-2-[(1R)-1-hydroxyethyl]butanoate; D-3-Hydroxyisovaline ethyl ester; (R,R)-3-Hydroxy-D-isovaline ethyl ester; 2-Amino-2-[(1R)-1-hydroxyethyl]butanoic acid ethyl ester, (2R)-rel-; Ethyl 2-amino-2-(1-hydroxyethyl)butyrate (D-isomer related)
EINECS	Contact for details

Quality Control

Our D-Isovaline, 3-Hydroxy-, Ethyl Ester, (4R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.