Description

D-Isovaline, 3-Hydroxy-, Ethyl Ester, (3S)-Rel- (9Ci) is a high-purity, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound is a valuable chiral building block and intermediate for advanced organic synthesis, particularly in pharmaceutical research and development. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-quality, stereochemically pure intermediates for the synthesis of complex molecules, peptides, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a standard or reagent in metabolic studies, enzyme-substrate interaction assays, and neurological research due to its structural similarity to natural amino acids.
• Peptide Synthesis: Serves as a protected or modified amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce specific structural features.
• Agrochemical Development: Employed as a building block in the synthesis of chiral pesticides, herbicides, and plant growth regulators.
• Asymmetric Catalysis: Can be utilized as a ligand precursor or chiral auxiliary in catalytic asymmetric synthesis to induce stereoselectivity.
• Fine Chemical Production: An intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Item	Details
Product Name	D-Isovaline, 3-Hydroxy-, Ethyl Ester, (3S)-Rel- (9Ci)
CAS No.	188124-78-9
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(3S)-rel-3-Hydroxy-D-isovaline ethyl ester; Ethyl (3S)-rel-3-hydroxy-D-isovaline; Ethyl 3-hydroxy-D-isovaline; D-3-Hydroxyisovaline ethyl ester; (S)-rel-Ethyl 3-hydroxy-2-amino-2-methylbutanoate; 2-Amino-2-methyl-3-hydroxybutyric acid ethyl ester, D-; 188124-78-9; (3S)-rel-3-Hydroxy-D-isovaline ethyl ester (9CI)
EINECS	Contact for details

Quality Control

Our D-Isovaline, 3-Hydroxy-, Ethyl Ester, (3S)-Rel- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.