Description

5-Bromo-2-Iodopyridin-3-Ol is a halogenated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique substitution pattern makes it an essential intermediate for medicinal chemists and R&D professionals developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring halogenated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Cross-Coupling Reactions: Ideal substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo substituents.
• Chemical Biology Probes: Used to create molecular probes and tags for studying biological systems and drug-target interactions.

Basic Information

Product Name	5-Bromo-2-Iodopyridin-3-Ol
CAS No.	188057-49-0
Molecular Formula	C5H3BrINO
Molecular Weight	299.89 g/mol
Synonyms	3-Hydroxy-5-bromo-2-iodopyridine; 5-Bromo-2-iodopyridin-3-ol; 2-Iodo-5-bromopyridin-3-ol; 3-Pyridinol, 5-bromo-2-iodo-; 188057-49-0; 5-Br-2-I-3-OH-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodopyridin-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.