Description

6-Chloro-2-Iodo-3-Hydroxypyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic building block in advanced organic chemistry. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists working on novel active ingredients, where precise halogen placement is key for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Building block for developing new generation herbicides and fungicides with targeted modes of action.
• Ligand and Catalyst Development: Used to create specialized pyridine-based ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Intermediate in the synthesis of functionalized organic molecules for electronic materials and organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in client-specific, multi-step synthetic routes for complex targets.

Basic Information

Product Name	6-Chloro-2-Iodo-3-Hydroxypyridine
CAS No.	188057-26-3
Molecular Formula	C5H3ClINO
Molecular Weight	255.44 g/mol
Synonyms	3-Hydroxy-6-chloro-2-iodopyridine; 2-Iodo-6-chloro-3-pyridinol; 6-Chloro-2-iodopyridin-3-ol; 2-Iodo-6-chloro-3-hydroxypyridine; 3-Pyridinol, 6-chloro-2-iodo-; 188057-26-3; 6-Chloro-2-iodo-3-pyridinol
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-2-Iodo-3-Hydroxypyridine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥97% (HPLC), with higher purity grades available upon request. Certificates of Analysis (COA) detailing batch-specific results for assay, related substances, and residual solvents are provided and traceable to in-house analytical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under low-light conditions to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.