Description

4-Iodo-Pyridin-3-Ol is a halogenated pyridine derivative, a versatile and valuable building block in advanced organic synthesis. This compound is particularly significant for introducing iodine functionality into complex molecular architectures, enabling key coupling reactions and structural modifications. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the iodine atom facilitates further functionalization.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form complex biaryl and conjugated systems.
• Chemical Biology & Proteomics: Employed as a tagging or labeling reagent for biomolecules in probe development and bioconjugation strategies.
• Organic Synthesis Building Block: Provides a handle for further derivatization to create libraries of novel heterocyclic compounds for screening and discovery.

Basic Information

Product Name	4-Iodo-Pyridin-3-Ol
CAS No.	188057-20-7
Molecular Formula	C5H4INO
Molecular Weight	220.99 g/mol
Synonyms	3-Hydroxy-4-iodopyridine; 4-Iodo-3-hydroxypyridine; 4-Iodo-3-pyridinol; 3-Pyridinol, 4-iodo-; 4-Iodopyridin-3-ol; 188057-20-7
EINECS	Contact for details

Quality Control

Our 4-Iodo-Pyridin-3-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.