Description

6 6'-Di-o-(tert-Butyldiphenylsilyl)-D- is a high-purity, organosilicon-protected derivative of a D-sugar, specifically designed as a critical synthetic intermediate. This compound matters for enabling sophisticated, multi-step organic syntheses where precise stereochemistry and functional group protection are paramount. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the production of novel active ingredients and chiral building blocks.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly nucleoside analogs and carbohydrate-based therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced, stereospecific pesticides and herbicides.
• Glycochemistry Research: Serves as a protected sugar derivative for studying glycosylation reactions and synthesizing complex oligosaccharides.
• Chiral Catalyst Ligand Precursor: Can be utilized to develop novel ligands for asymmetric catalysis.
• Advanced Material Development: Potential monomer or modifier in the creation of specialty polymers with specific stereochemical properties.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes requiring robust protection of sensitive hydroxyl groups.

Basic Information

Product Name	6 6'-Di-o-(tert-Butyldiphenylsilyl)-D-
CAS No.	187999-59-3
Molecular Formula	C44H54O10Si2
Molecular Weight	799.07 g/mol
Synonyms	1,2:3,4-Di-O-(1,1-dimethylethyl)-1,1,2,2-tetraphenyldisiloxanylidene-α-D-galactopyranose; Di-TBDPS-protected D-galactose derivative; 6,6'-Bis-O-(tert-butyldiphenylsilyl)-D-galactose; 1,2:3,4-Di-O-(tert-butyldiphenylsilylene)-α-D-galactopyranose; TBDPS-protected galactose dimer; D-Galactose, 1,2:3,4-bis-O-[(1,1-dimethylethyl)diphenylsilylene]-; 187999-59-3; α-D-Galactopyranose, 1,2:3,4-bis-O-[(1,1-dimethylethyl)diphenylsilylene]-
EINECS	Contact for details

Quality Control

Our 6 6'-Di-o-(tert-Butyldiphenylsilyl)-D- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to consistent quality and traceability supports your research and development needs from discovery to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.