Description

5-Amino-1-[4-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is a high-value, multi-functional pyrazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an amino group and a fluoromethylphenyl moiety, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags, enzyme inhibitors, and other molecular probes for diagnostic and research applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	5-Amino-1-[4-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester
CAS No.	187998-54-5
Molecular Formula	C14H16FN3O2
Molecular Weight	277.30 g/mol
Synonyms	Ethyl 5-Amino-1-[4-(fluoromethyl)phenyl]-1H-pyrazole-4-carboxylate; 1H-Pyrazole-4-carboxylic acid, 5-amino-1-[4-(fluoromethyl)phenyl]-, ethyl ester; 5-Amino-1-(4-fluoromethylphenyl)-1H-pyrazole-4-carboxylic acid ethyl ester; 187998-54-5; AKOS BRN 0971; ZINC000257019509; SCHEMBL11827579; CTK8G7115
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-1-[4-(Fluoromethyl)Phenyl]-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.