Description

3(2H)-Furanone, 2-(3-Chlorophenyl)-4-[4-(Ethylthio)-2-Pyridinyl]-5-(Methylamino)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile heterocyclic scaffold for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• API Development: Integral in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological pathways and identify new drug targets.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke synthesis services.

Basic Information

Product Name	3(2H)-Furanone, 2-(3-Chlorophenyl)-4-[4-(Ethylthio)-2-Pyridinyl]-5-(Methylamino)-
CAS No.	187592-24-1
Molecular Formula	C18H17ClN2O2S
Molecular Weight	360.86 g/mol
Synonyms	2-(3-Chlorophenyl)-4-[4-(ethylthio)-2-pyridinyl]-5-(methylamino)-3(2H)-furanone; 5-(Methylamino)-2-(3-chlorophenyl)-4-[4-(ethylthio)-2-pyridinyl]-3(2H)-furanone; 2-(3-Chlorophenyl)-5-(methylamino)-4-[4-(ethylthio)-2-pyridinyl]furan-3(2H)-one; 187592-24-1; Furan-3(2H)-one derivative
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced under strict quality management systems in facilities that adhere to cGMP principles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.