Description

3(2H)-Furanone, 4-(4-Bromo-2-Pyridinyl)-2-(2-Chlorophenyl)-5-(Methylamino)- is a high-purity, heterocyclic organic compound with a complex molecular structure, serving as a critical advanced intermediate in modern chemical synthesis. This compound matters for its role in constructing sophisticated molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up. Its precise structure offers a versatile scaffold for further functionalization, enabling the creation of targeted molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides due to its bioactive furanone and pyridine motifs.
• Material Science: Serves as a precursor for organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Synthesis: Acts as a versatile synthon in organic chemistry for constructing complex heterocyclic systems via cross-coupling and cyclization reactions.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3(2H)-Furanone, 4-(4-Bromo-2-Pyridinyl)-2-(2-Chlorophenyl)-5-(Methylamino)-
CAS No.	187592-01-4
Molecular Formula	C₁₇H₁₂BrClN₂O₂
Molecular Weight	415.65 g/mol
Synonyms	4-(4-Bromo-2-pyridinyl)-2-(2-chlorophenyl)-5-(methylamino)-3(2H)-furanone; 5-(Methylamino)-4-(4-bromo-2-pyridinyl)-2-(2-chlorophenyl)-2,5-dihydrofuran-3-one; 2-(2-Chlorophenyl)-4-(4-bromo-2-pyridinyl)-5-(methylamino)-3(2H)-furanone; 187592-01-4; 4-(4-Bromo-2-pyridyl)-2-(2-chlorophenyl)-5-(methylamino)furan-3-one; Methylamino-furanone derivative (4-bromo-2-pyridinyl)(2-chlorophenyl).
EINECS	Contact for details

Quality Control

Our 3(2H)-Furanone, 4-(4-Bromo-2-Pyridinyl)-2-(2-Chlorophenyl)-5-(Methylamino)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and residual solvent analysis by GC. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.