Description

3(2H)-Furanone, 5-(Methylamino)-4-(4-Methyl-2-Pyridinyl)-2-[3-(Trifluoromethyl)Phenyl]- is a high-value, complex heterocyclic compound featuring a fused furanone and pyridine structure with a trifluoromethylphenyl substituent. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and oncology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel small-molecule drug candidates, particularly in medicinal chemistry research.
• Drug Discovery Research: Used as a core scaffold for developing potential inhibitors or modulators of biological targets, leveraging its unique heterocyclic structure.
• Agrochemical Synthesis: Acts as a precursor for developing new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials due to its complex aromatic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	3(2H)-Furanone, 5-(Methylamino)-4-(4-Methyl-2-Pyridinyl)-2-[3-(Trifluoromethyl)Phenyl]-
CAS No.	187591-83-9
Molecular Formula	C18H15F3N2O2
Molecular Weight	348.32 g/mol
Synonyms	5-(Methylamino)-4-(4-methylpyridin-2-yl)-2-[3-(trifluoromethyl)phenyl]furan-3(2H)-one; 4-(4-Methyl-2-pyridinyl)-5-(methylamino)-2-[3-(trifluoromethyl)phenyl]-3(2H)-furanone; 187591-83-9; 5-Methylamino-4-(4-methyl-2-pyridyl)-2-[3-(trifluoromethyl)phenyl]-3(2H)-furanone; 2H-Furan-3-one, 5-(methylamino)-4-(4-methyl-2-pyridinyl)-2-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.