Description

3-Pyridinecarboxylic Acid, 5-Chloro-6-(1-Methylethoxy)- is a high-purity, substituted pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated and alkoxylated structure, which imparts specific reactivity and functionality for creating complex molecular architectures. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of functional organic materials, such as liquid crystals or organic semiconductors, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocyclic acids.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 5-Chloro-6-(1-Methylethoxy)-
CAS No.	187401-45-2
Molecular Formula	C9H10ClNO3
Molecular Weight	215.63 g/mol
Synonyms	5-Chloro-6-isopropoxynicotinic Acid; 5-Chloro-6-(1-methylethoxy)-3-pyridinecarboxylic Acid; 5-Chloro-6-isopropoxy-pyridine-3-carboxylic Acid; 5-Chloro-6-(propan-2-yloxy)nicotinic Acid; 3-Carboxy-5-chloro-6-isopropoxypyridine; 5-Chloro-6-isopropoxynicotinate; 6-Isopropoxy-5-chloronicotinic Acid; 187401-45-2
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxylic Acid, 5-Chloro-6-(1-Methylethoxy)- adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.