Description

5H-Imidazo[2,1-B][1,3]Oxazine, 6-Azido-6,7-Dihydro-2-Nitro-, (6S)- is a high-purity, chiral organic compound with the CAS number 187235-64-9. This specialized intermediate is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of structurally complex, stereochemically defined building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the discovery and production of advanced, high-performance crop protection chemicals.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or activity-based probes to study biological pathways.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Process Chemistry Optimization: Used by process chemists to scale up and optimize synthetic routes for cost-effective manufacturing.

Basic Information

Product Name	5H-Imidazo[2,1-B][1,3]Oxazine, 6-Azido-6,7-Dihydro-2-Nitro-, (6S)-
CAS No.	187235-64-9
Molecular Formula	C7H6N6O3
Molecular Weight	222.16 g/mol
Synonyms	(6S)-6-Azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine; 6-Azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine, (6S)-; 187235-64-9; (S)-6-Azido-2-nitro-5H,6H,7H-imidazo[2,1-b][1,3]oxazine; Azido-nitro-imidazoxazine; Chiral imidazoxazine azide; Nitroazidoimidazoxazine
EINECS	Contact for details

Quality Control

Every batch of (6S)-6-Azido-6,7-dihydro-2-nitro-5H-imidazo[2,1-b][1,3]oxazine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for each lot, supported by techniques such as HPLC, NMR, and chiral analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.