Description

tert-Butyl5-Cyano-6-Methylpyridin-2-Ylcarbamate CAS NO 187163-71-9 is a high-purity, protected pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and Contract Research: Essential reagent for methodological studies in organic chemistry and for contract research organizations (CROs) supporting client projects.
• Peptidomimetic Research: The carbamate and cyano groups make it a valuable scaffold in the design of peptide mimics for biological evaluation.

Basic Information

Product Name	tert-Butyl5-Cyano-6-Methylpyridin-2-Ylcarbamate
CAS No.	187163-71-9
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	tert-Butyl (5-cyano-6-methylpyridin-2-yl)carbamate; 2-Pyridinecarboxamide, 5-cyano-N-(1,1-dimethylethoxy)-6-methyl-; Carbamic acid, N-(5-cyano-6-methyl-2-pyridinyl)-, 1,1-dimethylethyl ester; 5-Cyano-6-methylpyridin-2-yl-carbamic acid tert-butyl ester; BOC-Protected 5-Cyano-6-methyl-2-aminopyridine; tert-Butoxycarbonyl-5-cyano-6-methyl-2-aminopyridine; 2-Amino-5-cyano-6-methylpyridine N-BOC derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl5-Cyano-6-Methylpyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.