Description

1H-Pyrazole-3-Carboxylic Acid, 4-(4-Methylphenyl)-, Ethyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a versatile synthon in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting inflammation, CNS disorders, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazole core's bioactivity.
• Material Science: Serves as a precursor for advanced organic materials, including ligands for catalysis and components for organic electronics.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthetic chemistry projects.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for various industrial applications.

Basic Information

Product Name	1H-Pyrazole-3-Carboxylic Acid, 4-(4-Methylphenyl)-, Ethyl Ester
CAS No.	187159-25-7
Molecular Formula	C13H14N2O2
Molecular Weight	230.26 g/mol
Synonyms	Ethyl 4-(p-tolyl)-1H-pyrazole-3-carboxylate; 4-(4-Methylphenyl)-1H-pyrazole-3-carboxylic acid ethyl ester; 1H-Pyrazole-3-carboxylic acid, 4-(4-methylphenyl)-, ethyl ester; Ethyl 4-(4-methylphenyl)-1H-pyrazole-3-carboxylate; 4-p-Tolyl-1H-pyrazole-3-carboxylic acid ethyl ester; 187159-25-7; 4-(4-Methylphenyl)pyrazole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-3-Carboxylic Acid, 4-(4-Methylphenyl)-, Ethyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.