Description

Sulforhodamine 101 Dhpe is a high-purity, fluorescent dye derivative specifically designed for advanced bioconjugation and labeling applications. Its core value lies in its ability to form stable conjugates with lipids and other biomolecules, enabling precise tracking and imaging in complex biological systems. This product is essential for researchers and manufacturers in the fields of biomedical research, diagnostic assay development, and advanced materials science who require reliable, high-performance fluorescent probes.

Application

• Fluorescent Labeling of Lipids and Membranes: Used to tag phospholipids like DOPE (dioleoylphosphatidylethanolamine) for studying membrane dynamics, fusion, and cellular uptake.
• Bioconjugation & Probe Synthesis: Serves as a critical reagent for creating custom fluorescent conjugates with proteins, antibodies, and other biomolecules.
• Live-Cell and Tissue Imaging: Enables long-term tracking of labeled entities in vitro and in vivo due to its photostability and bright fluorescence.
• Liposome & Nanoparticle Tracking: Ideal for labeling drug delivery vehicles such as liposomes to monitor their biodistribution and targeting efficiency.
• Diagnostic Assay Development: Utilized in the design of fluorescence-based diagnostic kits and biosensors for high-sensitivity detection.
• Flow Cytometry & Microscopy: Provides a strong red-emitting fluorophore for multicolor analysis in flow cytometry and confocal microscopy applications.

Basic Information

Product Name	Sulforhodamine 101 Dhpe
CAS No.	187099-99-6
Molecular Formula	C73H103N3O13S2
Molecular Weight	~1294.78 g/mol
Synonyms	Sulforhodamine 101-DOPE; SR101-DHPE; SR 101-labeled DOPE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(sulforhodamine 101); Sulforhodamine 101 phosphatidylethanolamine conjugate; Lissamine™ Rhodamine B DOPE; Fluorescent DOPE conjugate; Red fluorescent phospholipid label
EINECS	Contact for details

Quality Control

Every batch of Sulforhodamine 101 Dhpe undergoes rigorous analytical testing to ensure identity, purity, and performance consistency suitable for sensitive research applications. Our quality assurance includes HPLC purity analysis, spectroscopic verification (UV-Vis, Fluorescence), and functional testing in conjugation assays. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong oxidizers.

Specification

Item	Specification
Appearance	Dark red to purple solid or film
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Excitation Maximum (λex)	~585 nm
Emission Maximum (λem)	~605 nm
Extinction Coefficient (ε)	~85,000 cm-1M-1 (at λmax)
Solubility	Soluble in chloroform, DMSO, DMF; sparingly soluble in alcohols

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.