Description

Phenyl 3,4,6-Tri-o-Acetyl-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxyformamido)-β-D-Glucopyranoside is a sophisticated, high-purity thioglycoside building block used in advanced synthetic chemistry. This compound is critical for the controlled synthesis of complex oligosaccharides and glycoconjugates, where it acts as a key glycosyl donor with excellent stereoselectivity. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology research, and the development of novel therapeutics and diagnostics.

Application

• Glycosylation Reactions: Acts as a pivotal glycosyl donor in the stereoselective synthesis of O- and S-linked oligosaccharides and glycopeptides.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of carbohydrate-based drugs, including antibiotics and anticancer agents.
• Glycoconjugate Synthesis: Used for the preparation of neoglycoconjugates for biological studies and diagnostic assay development.
• Chemical Biology Probes: Enables the creation of tagged carbohydrate probes for studying glycan-protein interactions and metabolic pathways.
• Academic & Industrial R&D: A fundamental reagent for synthetic organic chemists in university laboratories and industrial R&D departments focusing on carbohydrate chemistry.
• Process Development: Employed in scaling up synthetic routes for complex carbohydrate targets during process chemistry optimization.

Basic Information

Product Name	Phenyl 3,4,6-Tri-o-Acetyl-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxyformamido)-β-D-Glucopyranoside
CAS No.	187022-49-7
Molecular Formula	C₂₁H₂₄Cl₃NO₉S
Molecular Weight	588.83 g/mol
Synonyms	Phenyl 2-Deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-1-thio-β-D-glucopyranoside 3,4,6-triacetate; 1-Thio-β-D-glucopyranoside, phenyl 3,4,6-tri-O-acetyl-2-deoxy-2-[(2,2,2-trichloroethoxy)formamido]-; Phenyl 2-Deoxy-2-[(trichloroethoxy)formamido]-1-thio-β-D-glucopyranoside Triacetate; Phenyl 3,4,6-Tri-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-1-thio-β-D-glucopyranoside; Troc-protected 2-Amino-2-deoxy-1-thioglucoside Triacetate; Glycosyl Donor for 2-Amino Sugar Synthesis; Thioglycoside Building Block
EINECS	Contact for details

Quality Control

Our production of Phenyl 3,4,6-Tri-o-Acetyl-2-Deoxy-1-Thio-2-(2,2,2-Trichloroethoxyformamido)-β-D-Glucopyranoside adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to ensure high chemical purity and structural integrity. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool environment. This compound is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.