Description

7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid, Methylester, (1S,2S,4S)- is a high-purity, stereochemically defined bicyclic lactone derivative that serves as a critical chiral building block in advanced organic synthesis. Its rigid, oxygen-containing bicyclic framework makes it a valuable precursor for constructing complex molecular architectures with precise spatial orientation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogs, and other bioactive molecules requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the bicyclic structure imparts specific biological activity.
• Material Science Monomer: Serves as a specialized monomer for creating polymers with unique thermal and mechanical properties derived from its strained bicyclic core.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multistep synthesis of flavors, fragrances, and other high-value specialty chemicals.
• Academic & R&D: A valuable tool for methodological development in organic chemistry, including studies on ring-opening reactions and cycloadditions.

Basic Information

Product Name	7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid, Methylester, (1S,2S,4S)-
CAS No.	186766-46-1
Molecular Formula	C8H10O3
Molecular Weight	154.16 g/mol
Synonyms	(1S,2S,4S)-7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester; (-)-7-Oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester, (1S-endo)-; Methyl (1S,2S,4S)-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylate; endo-(-)-Methyl 7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylate; Chiral Bicyclic Lactone Ester; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 7-oxa-, methyl ester, (1S,2S,4S)-
EINECS	Contact for details

Quality Control

Our production of 7-Oxabicyclo[2.2.1]Hept-5-Ene-2-Carboxylicacid, Methylester, (1S,2S,4S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.