Description

5-Amino-3-Bromo-2-Methylpyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a bromo substituent, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients. Its reliable reactivity profile is key for chemists developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogen and amino functionality for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized pyridine scaffolds.

Basic Information

Product Name	5-Amino-3-Bromo-2-Methylpyridine
CAS No.	186593-43-1
Molecular Formula	C6H7BrN2
Molecular Weight	187.04 g/mol
Synonyms	3-Bromo-2-methyl-5-aminopyridine; 2-Methyl-3-bromo-5-aminopyridine; 5-Amino-3-bromo-2-picoline; 3-Bromo-5-amino-2-picoline; 2-Picoline, 5-amino-3-bromo-; 186593-43-1; 5-Amino-3-bromo-2-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-3-Bromo-2-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.