Description

3-Bromo-2-Methyl-5-Nitropyridine CAS NO 186593-42-0 is a high-purity halogenated nitropyridine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring both bromine and nitro substituents on the pyridine ring, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides, herbicides, and fungicides, leveraging its reactive halogen and nitro groups.
• Material Science Research: Used in the synthesis of functionalized ligands, organic electronic materials, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, enabling further functionalization.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and complex organic compounds for various industrial applications.

Basic Information

Product Name	3-Bromo-2-Methyl-5-Nitropyridine
CAS No.	186593-42-0
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	3-Bromo-2-methyl-5-nitropyridine; 2-Methyl-3-bromo-5-nitropyridine; 5-Nitro-3-bromo-2-methylpyridine; Pyridine, 3-bromo-2-methyl-5-nitro-; 186593-42-0; 3-Br-2-Me-5-NO2-Pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Methyl-5-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.