Description

3-Benzyloxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its benzyl-protected oxygen and electron-withdrawing trifluoromethyl group. This compound is essential for medicinal chemistry and advanced material science, where its unique structure enables precise modulation of molecular properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for constructing complex ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized pyridine derivatives.

Basic Information

Product Name	3-Benzyloxy-5-(Trifluoromethyl)Pyridine
CAS No.	186593-13-5
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	5-(Trifluoromethyl)-3-(phenylmethoxy)pyridine; 3-(Benzyloxy)-5-(trifluoromethyl)pyridine; Pyridine, 3-(phenylmethoxy)-5-(trifluoromethyl)-; 3-Benzyloxy-5-trifluoromethylpyridine; 186593-13-5; 3-(Benzyloxy)-5-(trifluoromethyl)pyridine; 3-Benzyloxy-5-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Benzyloxy-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.