Description

3-Pyridinamine,5-[(2S)-2-Azetidinylmethoxy]-2-Fluoro-(9Ci) is a sophisticated chiral building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a fluorinated pyridine core with an azetidine moiety, enabling precise structural modifications in target molecules. This compound is primarily needed by research and development teams within the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom and heterocyclic structures can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed as a molecular probe or a building block for labeling agents in proteomics and diagnostic assay development.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and advanced polymers due to its conjugated system.

Basic Information

Product Name	3-Pyridinamine,5-[(2S)-2-Azetidinylmethoxy]-2-Fluoro-(9Ci)
CAS No.	186590-42-1
Molecular Formula	C9H12FN3O
Molecular Weight	197.21 g/mol
Synonyms	2-Fluoro-5-[(2S)-2-azetidinylmethoxy]-3-pyridinamine; (S)-2-Fluoro-5-(2-azetidinylmethoxy)-3-pyridinamine; 5-[(2S)-2-Azetidinylmethoxy]-2-fluoro-3-pyridinamine; 186590-42-1; (S)-5-(Azetidin-2-ylmethoxy)-2-fluoropyridin-3-amine; Azetidine, 2-[[(6-amino-5-fluoro-3-pyridinyl)oxy]methyl]-, (2S)-
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinamine,5-[(2S)-2-Azetidinylmethoxy]-2-Fluoro-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the product in a cool, dry place at temperatures between 2°C and 8°C. The compound may be hygroscopic; handle and store under an inert atmosphere such as nitrogen or argon for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.