Description

2-Methylpropyl n-(2-Chloropyridine-3-Sulfonyl)-n-(3-Methoxy-5-Methylpyrazin-2-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical manufacturers and R&D organizations engaged in the development of new chemical entities (NCEs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new-generation pesticides and herbicides, leveraging its pyridine and pyrazine moieties.
• Chemical Synthesis: Used in organic synthesis for constructing complex sulfonamide and carbamate-containing molecules in academic and industrial research.
• Bioconjugate Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic agents due to its reactive functional groups.

Basic Information

Product Name	2-Methylpropyl n-(2-Chloropyridine-3-Sulfonyl)-n-(3-Methoxy-5-Methylpyrazin-2-Yl)Carbamate
CAS No.	186497-45-0
Molecular Formula	C15H17ClN4O5S
Molecular Weight	400.84 g/mol
Synonyms	Isobutyl N-(2-chloropyridine-3-sulfonyl)-N-(3-methoxy-5-methylpyrazin-2-yl)carbamate; 2-Methylpropyl (2-chloropyridin-3-yl)sulfonyl(3-methoxy-5-methylpyrazin-2-yl)carbamate; Carbamic acid, N-(2-chloro-3-pyridinyl)sulfonyl-N-(3-methoxy-5-methyl-2-pyrazinyl)-, 2-methylpropyl ester; 186497-45-0; Isobutyl carbamate derivative of chloropyridine sulfonyl methoxy methylpyrazine.
EINECS	Contact for details

Quality Control

Our 2-Methylpropyl n-(2-Chloropyridine-3-Sulfonyl)-n-(3-Methoxy-5-Methylpyrazin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.